Wednesday, March 25, 2020

Why professionals choose to enter helping field free essay sample

Professionals choose to enter this field for various reasons, some personal, professional, or because they simply want to help others and give them a chance at a better life. Majority of the professionals get a sense of approval when helping others whether offering direct or indirect assistance. Some people chose to enter the helping field because many people around have children with disabilities or dysfunctions within the home and want to make a difference with them, helping them to have that support of the ones that have had the same experience. By learning more of how to help them and to find the best way to support them we can help many of the families around to understand what they are going through as well as learning techniques to help themselves with their child or children. Others chose this field because it hurt reading about so many cases of child abuse from parents of infants, small kids, and children with special needs that were assigned to case workers that knew the kids needed some type of help and they falsely signed papers saying they checked on the child but the children passed away. We will write a custom essay sample on Why professionals choose to enter helping field or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page Feelings of being one could be one of the many caseworkers that actually do care of the outcome of children. Some professionals have actual personal experiences with family of people with different issues. All of these aspects of life have given professionals the motivation to become a worker in the helping field to help those needing help. When in need, we should be able to ask for help and be treated with respect, instead we have seen the opposite. Wanting to be the change in the system, wanting to be the one that cares about these people and helps them along their journey is also I great motivating factor to join the helping field. These are only a few reasons professionals decided to join the helping field. When people chose this field they could have been helped themselves or know someone that assisted and got great results. In the end, the main reason people choose to enter the helping field is to actually help others, getting a satisfaction and sense of urgency in the world.

Friday, March 6, 2020

SiRNA and miRNA Essay Example

SiRNA and miRNA Essay Example SiRNA and miRNA Essay SiRNA and miRNA Essay SiRNA (small interfering RNA) belongs to a class of 20-25 nucleotide-long and double-stranded RNA molecules. It is known that siRNA plays important role in biological processes. For example, it is involved in the interference of RNA pathway and is responsible for expression of a specific gene there. Additionally, its role is to act in RNAi-related pathway. It means that siRNA acts as antiviral mechanism shaping the chromatin structure of a genome. It is necessary to admit that siRNA has a well defined structure. It is a short double-strand of RNA having overhangs on both ends. SiRNA’s strands have 5’ phosphate group and 3’ hydroxyl group. Biologists claim that siRNA’s structure results from the processing by dicer (i.e. enzyme being responsible for converting long dsRNAs and small hairpin RNAs into siRNAs). Transfection methods are involved to make siRNAs be introduced into cells with the purpose to cause knockdown of a gene of interest. Therefore, siRNA p lays important role in gene expressions and validation of drug target. First siRNA was discovered as a past of â€Å"post-transcriptional gene silencing†, whereas miRNA was discovered as a part of primary microRNA   Comparing siRNA and miRNA, siRNA is a short inferring RNA being generated mostly in vitro or can be synthesized, whereas miRNA is a short double-stranded RNA molecule resulted from dicing long pre-miRNA molecules. Actually, miRNA differs from siRNA as it is obtained from single-stranded RNA precursors. Additionally, in contrast to siRNA, miRNA shows only partial complementary to mRNA targets. MirNA is known to perform wide range of functions; especially it is responsible for cell growth and adoptosis as well as for cell development, insulin secretion and neuronal remodeling. MiRNAs are implicated in diseases. Both siRNA and miRNA are able to regulate expression of a specific gene, though miRNA regulates it at the level of translational inhibition. Finally, it is admitted that miRNA can also guide mRNA in a similar way to siRNA. Loewenstein, Werner. Molecular Information, Cell Communication, and the Foundations of Life. New York: Oxford University Press, 1999.